When you install the driver packs you download from AMD, you’re automatically enrolled in their User Experience Program. To opt out [leave] you have to open the AMD driver settings app [right click the desktop or Taskbar Icon], click Settings [the gear-like icon on the upper right], click Preferences, scroll down to the AMD User Experience Program, then click leave in the drop down menu box. Now you can go to ProgramData\ AMD\ PPC\ folder [you must enable Show hidden files… in File Explorer -> View Options if it’s not enabled already] and delete the 4 .csv files. They can total 1, or several GB, and it wouldn’t hurt to check that folder from time to time to make sure they haven’t returned & continued to grow.
Another way these driver packs can waste space is with old versions of the driver left behind in Windows\ System32\ DriverStore\ FileRepository. Each one takes up around 1GB. Unlike many [most?] other driver packages, installing a new AMD graphics driver does not remove the old one from this folder, where copies of all installed drivers, plus some that come with Windows are stored. Often, but not always, running Disk Cleanup [right click the Windows drive in File Explorer & select Properties], selecting Clean up system files will give you the option to delete old driver packs. You can *usually* take ownership of these folders containing old drivers and manually delete them also. The free Wiz Tree [also available in a portable version] is a quick way to find out if there are old AMD driver packs hanging around.
Now, I just said *usually* because Win11 screwed thing up. A stripped-down version of the AMD graphics drivers is available via Windows Update. In Win10, and currently in Win11 you’re given a choice whether you want to install them or not, but in Win11 for quite a while that choice was not available – you got them whether you wanted to or not. If you reinstalled the full driver pack from AMD, you’re probably OK. If you let it slide each time Windows Update installed a new version, you may have several old driver versions in that FileRepository folder, and Windows may continue to use those old versions so you cannot delete them. You have to install the full driver pack from AMD, which in this case by default will uninstall the Windows Update versions, including those old drivers. It’ll take 2 Windows restarts, and on this PC the 1st restart needs to be a shut down – with just a restart the GPU won’t work, with an out of bounds message on the monitor.